The following documents outline the requirements for conducting research using human embryonic stem cells. The requirements are complex and so you are encouraged to contact MSU’s Institutional Stem Cell Research Committee for assistance early.

State of Michigan

  • Constitution of Michigan of 1963, Article I § 27 Human Embryo and Embryonic Stem Cell Research (Eff. December 19, 2008) permits research on human embryos subject to the requirements of federal law and only under additional specified limitations and requirements.
  • The Human Cloning Funding Prohibition Act, Act 111 of 1998 (Eff. March 23, 1999) prohibits the expenditure of state funds (Michigan) for the purpose of human cloning.


  • Presidential Documents, Executive Order 13505 of March 9, 2009, Removing Barriers to Responsible Scientific Research Involving Human Stem Cells removes limitations on scientific inquiry and expands NIH support for the exploration of human stem cell research.
  • Presidential Documents, Memorandum of July 30, 2009, Guidelines for Human Stem Cell Research directs the heads of executive departments and agencies that support and conduct stem cell research to adopt the NIH Guidelines for Human Stem Cell Research to the fullest extent practicable in light of legal authorities and obligations.
  • National Institutes of Health Guidelines for Human Stem Cell Research (July 7, 2009). These guidelines apply to expenditure of NIH funds for research using human embryonic stem cells and certain uses of induced pluripotent stem cells.
  • Omnibus Appropriations Act, Section 509. Prohibition of the use of federal funds to create human embryo(s) for research purposes or destroy human embryo(s).

National Academy of Sciences

National Academy of Sciences Guidelines for Human Stem Cell Research.

  • 2010 Amendments
  • 2008 Amendments
  • 2007 Amendments
  • 2005 Guidelines

International Society for Stem Cell Research

  • International Society for Stem Cell Research Guidelines for the Conduct of Human Embryonic Stem Cell Research (December 21, 2006).